Registered Nurse salary in South Carolina
Registered nurses in South Carolina earn a median $82,360 a year, 16% below the national median of $97,550. That ranks #39 of 51 states. After taxes, a single filer keeps about $64,227.
Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1141. Taxes for tax year 2026.
| Yearly | Monthly | Every 2 weeks | Hourly | |
|---|---|---|---|---|
| Median pay | $82,360 | $6,863 | $3,168 | $39.60 |
| Average pay | $87,670 | $7,306 | $3,372 | $42.15 |
| Take-home (median) | $64,227 | $5,352 | $2,470 | $30.88 |
Where the money goes
| Item | Per year |
|---|---|
| Federal income tax | $9,289 |
| Social Security and Medicare | $6,301 |
| South Carolina income tax | $2,543 |
| Take-home | $64,227 |
South Carolina's prices are 6% below the U.S. average, so the median take-home buys what $68,509 buys in an average-priced state. The South Carolina minimum wage is $7.25; the median registered nurse earns 5.5 times that.
Registered Nurse pay in South Carolina vs. neighboring states
| State | Median salary | Take-home | Buying power |
|---|---|---|---|
| South Carolina | $82,360 | $64,227 | $68,509 |
| Georgia | $93,550 | $70,723 | $73,445 |
| North Carolina | $84,350 | $65,313 | $69,242 |
Frequently asked questions
- How much do registered nurses make in South Carolina?
- The median salary is $82,360 a year ($39.60 an hour), and the average is $87,670, per BLS data for May 2025.
- How much do registered nurses take home in South Carolina?
- About $64,227 a year after federal and South Carolina taxes, or $2,470 every two weeks, for a single filer at the median salary.
- Do registered nurses earn more in South Carolina than the national average?
- South Carolina ranks #39 of 51 for median pay, 16% below the U.S. median of $97,550. Adjusted for prices and taxes it ranks #45.