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Registered Nurse salary in Missouri

Registered nurses in Missouri earn a median $81,780 a year, 16% below the national median of $97,550. That ranks #40 of 51 states. After taxes, a single filer keeps about $63,456.

Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1141. Taxes for tax year 2026.

YearlyMonthlyEvery 2 weeksHourly
Median pay$81,780$6,815$3,145$39.32
Average pay$85,900$7,158$3,304$41.30
Take-home (median)$63,456$5,288$2,441$30.51

Where the money goes

ItemPer year
Federal income tax$9,162
Social Security and Medicare$6,256
Missouri income tax$2,906
Take-home$63,456

Missouri's prices are 9% below the U.S. average, so the median take-home buys what $69,872 buys in an average-priced state. The Missouri minimum wage is $15.00; the median registered nurse earns 2.6 times that.

Registered Nurse pay in Missouri vs. neighboring states

StateMedian salaryTake-homeBuying power
Missouri$81,780$63,456$69,872
Arkansas$78,940$61,931$71,237
Illinois$95,990$71,752$71,782
Iowa$78,630$61,810$70,429
Kansas$79,320$61,005$67,732
Kentucky$81,040$63,123$70,013
Nebraska$84,730$65,462$72,652
Oklahoma$82,920$63,978$72,833
Tennessee$81,500$66,165$72,021

Frequently asked questions

How much do registered nurses make in Missouri?
The median salary is $81,780 a year ($39.32 an hour), and the average is $85,900, per BLS data for May 2025.
How much do registered nurses take home in Missouri?
About $63,456 a year after federal and Missouri taxes, or $2,441 every two weeks, for a single filer at the median salary.
Do registered nurses earn more in Missouri than the national average?
Missouri ranks #40 of 51 for median pay, 16% below the U.S. median of $97,550. Adjusted for prices and taxes it ranks #38.