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Registered Nurse salary in Mississippi

Registered nurses in Mississippi earn a median $77,090 a year, 21% below the national median of $97,550. That ranks #50 of 51 states. After taxes, a single filer keeps about $60,711.

Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1141. Taxes for tax year 2026.

YearlyMonthlyEvery 2 weeksHourly
Median pay$77,090$6,424$2,965$37.06
Average pay$78,950$6,579$3,037$37.96
Take-home (median)$60,711$5,059$2,335$29.19

Where the money goes

ItemPer year
Federal income tax$8,130
Social Security and Medicare$5,897
Mississippi income tax$2,352
Take-home$60,711

Mississippi's prices are 13% below the U.S. average, so the median take-home buys what $69,821 buys in an average-priced state. The Mississippi minimum wage is $7.25; the median registered nurse earns 5.1 times that.

Registered Nurse pay in Mississippi vs. neighboring states

StateMedian salaryTake-homeBuying power
Mississippi$77,090$60,711$69,821
Alabama$77,080$59,467$66,950
Arkansas$78,940$61,931$71,237
Louisiana$80,230$63,251$71,708
Tennessee$81,500$66,165$72,021

Frequently asked questions

How much do registered nurses make in Mississippi?
The median salary is $77,090 a year ($37.06 an hour), and the average is $78,950, per BLS data for May 2025.
How much do registered nurses take home in Mississippi?
About $60,711 a year after federal and Mississippi taxes, or $2,335 every two weeks, for a single filer at the median salary.
Do registered nurses earn more in Mississippi than the national average?
Mississippi ranks #50 of 51 for median pay, 21% below the U.S. median of $97,550. Adjusted for prices and taxes it ranks #39.