Wagevane

Pharmacist salary in South Dakota

Pharmacists in South Dakota earn a median $146,790 a year, 4% above the national median of $140,910. That ranks #13 of 51 states. After taxes, a single filer keeps about $111,597.

Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1051. Taxes for tax year 2026.

YearlyMonthlyEvery 2 weeksHourly
Median pay$146,790$12,233$5,646$70.57
Average pay$142,330$11,861$5,474$68.43
Take-home (median)$111,597$9,300$4,292$53.65

Where the money goes

ItemPer year
Federal income tax$23,964
Social Security and Medicare$11,229
South Dakota income tax$0
Take-home$111,597

South Dakota's prices are 11% below the U.S. average, so the median take-home buys what $125,976 buys in an average-priced state. The South Dakota minimum wage is $11.85; the median pharmacist earns 6.0 times that.

Pharmacist pay in South Dakota vs. neighboring states

StateMedian salaryTake-homeBuying power
South Dakota$146,790$111,597$125,976
Iowa$138,860$101,552$115,713
Minnesota$159,740$110,039$111,578
Montana$142,080$101,711$107,466
Nebraska$139,330$101,038$112,136
North Dakota$142,040$106,840$120,100
Wyoming$139,550$106,648$115,058

Frequently asked questions

How much do pharmacists make in South Dakota?
The median salary is $146,790 a year ($70.57 an hour), and the average is $142,330, per BLS data for May 2025.
How much do pharmacists take home in South Dakota?
About $111,597 a year after federal taxes, or $4,292 every two weeks, for a single filer at the median salary.
Do pharmacists earn more in South Dakota than the national average?
South Dakota ranks #13 of 51 for median pay, 4% above the U.S. median of $140,910. Adjusted for prices and taxes it ranks #1.