Wagevane

Nurse Practitioner salary in South Carolina

Nurse practitioners in South Carolina earn a median $123,290 a year, 7% below the national median of $132,300. That ranks #48 of 51 states. After taxes, a single filer keeps about $90,859.

Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1171. Taxes for tax year 2026.

YearlyMonthlyEvery 2 weeksHourly
Median pay$123,290$10,274$4,742$59.27
Average pay$124,170$10,348$4,776$59.70
Take-home (median)$90,859$7,572$3,495$43.68

Where the money goes

ItemPer year
Federal income tax$18,324
Social Security and Medicare$9,432
South Carolina income tax$4,676
Take-home$90,859

South Carolina's prices are 6% below the U.S. average, so the median take-home buys what $96,917 buys in an average-priced state. The South Carolina minimum wage is $7.25; the median nurse practitioner earns 8.2 times that.

Nurse Practitioner pay in South Carolina vs. neighboring states

StateMedian salaryTake-homeBuying power
South Carolina$123,290$90,859$96,917
Georgia$129,430$94,021$97,641
North Carolina$128,990$94,793$100,495

Frequently asked questions

How much do nurse practitioners make in South Carolina?
The median salary is $123,290 a year ($59.27 an hour), and the average is $124,170, per BLS data for May 2025.
How much do nurse practitioners take home in South Carolina?
About $90,859 a year after federal and South Carolina taxes, or $3,495 every two weeks, for a single filer at the median salary.
Do nurse practitioners earn more in South Carolina than the national average?
South Carolina ranks #48 of 51 for median pay, 7% below the U.S. median of $132,300. Adjusted for prices and taxes it ranks #36.