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Nurse Practitioner salary in Mississippi

Nurse practitioners in Mississippi earn a median $124,730 a year, 6% below the national median of $132,300. That ranks #47 of 51 states. After taxes, a single filer keeps about $92,262.

Source: BLS Occupational Employment and Wage Statistics, May 2025, SOC 29-1171. Taxes for tax year 2026.

YearlyMonthlyEvery 2 weeksHourly
Median pay$124,730$10,394$4,797$59.97
Average pay$125,340$10,445$4,821$60.26
Take-home (median)$92,262$7,688$3,549$44.36

Where the money goes

ItemPer year
Federal income tax$18,669
Social Security and Medicare$9,542
Mississippi income tax$4,257
Take-home$92,262

Mississippi's prices are 13% below the U.S. average, so the median take-home buys what $106,105 buys in an average-priced state. The Mississippi minimum wage is $7.25; the median nurse practitioner earns 8.3 times that.

Nurse Practitioner pay in Mississippi vs. neighboring states

StateMedian salaryTake-homeBuying power
Mississippi$124,730$92,262$106,105
Alabama$105,750$78,203$88,043
Arkansas$125,660$92,993$106,966
Louisiana$125,600$93,732$106,264
Tennessee$117,590$91,555$99,657

Frequently asked questions

How much do nurse practitioners make in Mississippi?
The median salary is $124,730 a year ($59.97 an hour), and the average is $125,340, per BLS data for May 2025.
How much do nurse practitioners take home in Mississippi?
About $92,262 a year after federal and Mississippi taxes, or $3,549 every two weeks, for a single filer at the median salary.
Do nurse practitioners earn more in Mississippi than the national average?
Mississippi ranks #47 of 51 for median pay, 6% below the U.S. median of $132,300. Adjusted for prices and taxes it ranks #13.